Pre-Clinical Autoimmunity in Lupus Relatives: Self-Reported Questionnaires and Immune Dysregulation Distinguish Relatives Who Develop Incomplete or Classified Lupus From Clinically Unaffected Relatives and Unaffected, Unrelated Individuals

Systemic lupus erythematosus (SLE) is propelled by pathogenic autoantibody (AutoAb) and immune pathway dysregulation. Identifying populations at risk of reaching classified SLE is essential to curtail inflammatory damage. Lupus blood relatives (Rel) have an increased risk of developing SLE. We teste...

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Detalles Bibliográficos
Autores principales: Munroe, Melissa E., Young, Kendra A., Guthridge, Joel M., Kamen, Diane L., Gilkeson, Gary S., Weisman, Michael H., Ishimori, Mariko L., Wallace, Daniel J., Karp, David R., Harley, John B., Norris, Jill M., James, Judith A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9203691/
https://www.ncbi.nlm.nih.gov/pubmed/35720322
http://dx.doi.org/10.3389/fimmu.2022.866181

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