Adiponectin Ameliorates GMH-Induced Brain Injury by Regulating Microglia M1/M2 Polarization Via AdipoR1/APPL1/AMPK/PPARγ Signaling Pathway in Neonatal Rats

Adiponectin (APN), a fat-derived plasma hormone, is a classic anti-inflammatory agent. Multiple studies have demonstrated the beneficial role of APN in acute brain injury, but the effect of APN in germinal matrix hemorrhage (GMH) is unclear, and the underlying molecular mechanisms remain largely und...

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Detalles Bibliográficos
Autores principales: Xu, Ningbo, Li, Xifeng, Weng, Jun, Wei, Chunhua, He, Zhenyan, Doycheva, Desislava Met, Lenahan, Cameron, Tang, Wenhui, Zhou, Jian, Liu, Yanchao, Xu, Qiang, Liu, Yahong, He, Xuying, Tang, Jiping, Zhang, John H., Duan, Chuanzhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9203698/
https://www.ncbi.nlm.nih.gov/pubmed/35720361
http://dx.doi.org/10.3389/fimmu.2022.873382

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