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FUNDC2 promotes liver tumorigenesis by inhibiting MFN1-mediated mitochondrial fusion

Mitochondria generate ATP and play regulatory roles in various cellular activities. Cancer cells often exhibit fragmented mitochondria. However, the underlying mechanism remains elusive. Here we report that a mitochondrial protein FUN14 domain containing 2 (FUNDC2) is transcriptionally upregulated i...

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Detalles Bibliográficos
Autores principales:	Li, Shuaifeng, Han, Shixun, Zhang, Qi, Zhu, Yibing, Zhang, Haitao, Wang, Junli, Zhao, Yang, Zhao, Jianhui, Su, Lin, Li, Li, Zhou, Dawang, Ye, Cunqi, Feng, Xin-Hua, Liang, Tingbo, Zhao, Bin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9203792/ https://www.ncbi.nlm.nih.gov/pubmed/35710796 http://dx.doi.org/10.1038/s41467-022-31187-6

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