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Ketone body 3-hydroxybutyrate enhances adipocyte function

Ketone bodies, including 3HBA, are endogenous products of fatty acid oxidation, and Hmgcs2 is the first rate-limiting enzyme of ketogenesis. From database analysis and in vivo and in vitro experiments, we found that adipose tissue and adipocytes express Hmgcs2, and that adipocytes produce and secret...

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Detalles Bibliográficos
Autores principales: Nishitani, Shigeki, Fukuhara, Atsunori, Tomita, Issei, Kume, Shinji, Shin, Jihoon, Okuno, Yosuke, Otsuki, Michio, Maegawa, Hiroshi, Shimomura, Iichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9203800/
https://www.ncbi.nlm.nih.gov/pubmed/35710581
http://dx.doi.org/10.1038/s41598-022-14268-w

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