Cargando…

Immune Subtypes in LUAD Identify Novel Tumor Microenvironment Profiles With Prognostic and Therapeutic Implications

The six transcriptomic immune subtypes (ISs) (C1 - C6) were reported to have complex and different interplay between TME and cancer cells in TCGA (The Cancer Genome Atlas) pan-cancer cohort. Our study specifically explored how the consequence of interplay determines the prognosis and the response to...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Feng, Gao, Xuan, Wang, Peiyuan, He, Hao, Chen, Peng, Liu, Zhentian, Chen, Yujie, Zhou, Hang, Chen, Weijie, Yi, Xin, Xia, Xuefeng, Liu, Shuoyan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9203850/ https://www.ncbi.nlm.nih.gov/pubmed/35720373 http://dx.doi.org/10.3389/fimmu.2022.877896

Ejemplares similares

CCND1 Amplification Profiling Identifies a Subtype of Melanoma Associated With Poor Survival and an Immunosuppressive Tumor Microenvironment
por: Liu, Jun, et al.
Publicado: (2022)

STK24 Promotes Progression of LUAD and Modulates the Immune Microenvironment
por: Li, Yadong, et al.
Publicado: (2023)

Distinct subtypes of endometriosis identified based on stromal-immune microenvironment and gene expression: implications for hormone therapy
por: Wang, Yuning, et al.
Publicado: (2023)

Gene Expression Classifier Reveals Prognostic Osteosarcoma Microenvironment Molecular Subtypes
por: Song, Yi-Jiang, et al.
Publicado: (2021)

The Clinical Prediction Value of the Ubiquitination Model Reflecting the Immune Traits in LUAD
por: Che, Yinggang, et al.
Publicado: (2022)

Differentiated regulation of immune-response related genes between LUAD and LUSC subtypes of lung cancers
por: Chen, Mengzhu, et al.
Publicado: (2016)

Immune Microenvironment in Glioblastoma Subtypes
por: Chen, Zhihong, et al.
Publicado: (2018)

Regulatory T-cells-related signature for identifying a prognostic subtype of hepatocellular carcinoma with an exhausted tumor microenvironment
por: Zhang, Genhao
Publicado: (2022)

Deciphering the Prognostic Implications of the Components and Signatures in the Immune Microenvironment of Pancreatic Ductal Adenocarcinoma
por: Tang, Rong, et al.
Publicado: (2021)

TAGAP expression influences CD4+ T cell differentiation, immune infiltration, and cytotoxicity in LUAD through the STAT pathway: implications for immunotherapy
por: Xu, Zhanyu, et al.
Publicado: (2023)

Macrophage-related molecular subtypes in lung adenocarcinoma identify novel tumor microenvironment with prognostic and therapeutic implications
por: Wen, Heng, et al.
Publicado: (2022)

TP53 and CDKN2A mutations in patients with early-stage lung squamous cell carcinoma: an analysis of the correlations and prognostic outcomes
por: Wang, Peiyuan, et al.
Publicado: (2021)

Heterogeneity of tumor immune microenvironment in malignant and metastatic change in LUAD is revealed by single-cell RNA sequencing
por: Wang, Haiqiang, et al.
Publicado: (2023)

A Machine-Learning Approach to Developing a Predictive Signature Based on Transcriptome Profiling of Ground-Glass Opacities for Accurate Classification and Exploring the Immune Microenvironment of Early-Stage LUAD
por: Zhao, Zhenyu, et al.
Publicado: (2022)

Identification and validation of a classifier based on hub aging-related genes and aging subtypes correlation with immune microenvironment for periodontitis
por: Peng, Limin, et al.
Publicado: (2022)

Comprehensive Analysis Identifies and Validates the Tumor Microenvironment Subtypes to Predict Anti-Tumor Therapy Efficacy in Hepatocellular Carcinoma
por: Zhang, Haohan, et al.
Publicado: (2022)

Immune microenvironment infiltration landscape and immune-related subtypes in prostate cancer
por: Wu, Wei, et al.
Publicado: (2023)

Genomic and immunogenomic analysis of three prognostic signature genes in LUAD
por: Feng, Hai-Ming, et al.
Publicado: (2023)

Identification of N7-methylguanosine related subtypes and construction of prognostic model in gastric cancer
por: Li, Xiaoxiao, et al.
Publicado: (2022)

Identifying enhancer-driven subtype-specific prognostic markers in breast cancer based on multi-omics data
por: Zhao, Hongying, et al.
Publicado: (2022)

Identification of disulfidptosis related subtypes, characterization of tumor microenvironment infiltration, and development of DRG prognostic prediction model in RCC, in which MSH3 is a key gene during disulfidptosis
por: Xu, Kai, et al.
Publicado: (2023)

Identification of pyroptosis-related subtypes and establishment of prognostic model and immune characteristics in asthma
por: Yang, Fan, et al.
Publicado: (2022)

Establishment and validation of individualized clinical prognostic markers for LUAD patients based on autophagy-related genes
por: Fei, Yuchang, et al.
Publicado: (2022)

Upregulation of deubiquitinase PSMD14 in lung adenocarcinoma (LUAD) and its prognostic significance
por: Zhang, Ling, et al.
Publicado: (2020)

Molecular subtypes based on Wnt-signaling gene expression predict prognosis and tumor microenvironment in hepatocellular carcinoma
por: Xu, Weifeng, et al.
Publicado: (2022)

CEP192 is a novel prognostic marker and correlates with the immune microenvironment in hepatocellular carcinoma
por: Liu, Yanli, et al.
Publicado: (2022)

Identification of cuproptosis-related subtypes, characterization of immune microenvironment infiltration, and development of a prognosis model for osteoarthritis
por: Nong, Jiao, et al.
Publicado: (2023)

MDFI is a novel biomarker for poor prognosis in LUAD
por: Chen, Pengyu, et al.
Publicado: (2022)

Functional proteomics identify mannitol metabolism in serum resistance and therapeutic implications in Vibrio alginolyticus
por: Kou, Tian-shun, et al.
Publicado: (2022)

Recruitment mechanisms and therapeutic implications of tumor-associated macrophages in the glioma microenvironment
por: Zhou, Xianzhe, et al.
Publicado: (2023)

Construction of an immune-related lncRNA signature as a novel prognosis biomarker for LUAD
por: Chen, Hang, et al.
Publicado: (2021)

Identification of the key genes and characterizations of Tumor Immune Microenvironment in Lung Adenocarcinoma (LUAD) and Lung Squamous Cell Carcinoma (LUSC)
por: Zhang, Lemeng, et al.
Publicado: (2020)

A seven-gene prognostic signature predicts overall survival of patients with lung adenocarcinoma (LUAD)
por: Al-Dherasi, Aisha, et al.
Publicado: (2021)

Combined signature of N7-methylguanosine regulators with their related genes and the tumor microenvironment: a prognostic and therapeutic biomarker for breast cancer
por: Li, Tingjun, et al.
Publicado: (2023)

Identification of potential diagnostic and prognostic biomarkers for LUAD based on TCGA and GEO databases
por: Zheng, Qiangqiang, et al.
Publicado: (2021)

High-dose chemotherapy sensitizes locally advanced esophageal squamous cell carcinoma to PD-1 blockade for a higher pathological complete response rate and survival
por: Wang, Peiyuan, et al.
Publicado: (2023)

Single-Cell Transcriptomics Revealed Subtype-Specific Tumor Immune Microenvironments in Human Glioblastomas
por: Xiao, Yong, et al.
Publicado: (2022)

Identification of Ferroptosis-Related Prognostic Signature and Subtypes Related to the Immune Microenvironment for Breast Cancer Patients Receiving Neoadjuvant Chemotherapy
por: Xu, Yuhao, et al.
Publicado: (2022)

Identifying a baicalein-related prognostic signature contributes to prognosis prediction and tumor microenvironment of pancreatic cancer
por: Zhang, Citing, et al.
Publicado: (2023)

PBK correlates with prognosis, immune escape and drug response in LUAD
por: Ma, Hongyu, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_3obvpl98g6obpk8gvj8m8kfp5d