Rapamycin Dampens Inflammatory Properties of Bone Marrow ILC2s in IL-33-Induced Eosinophilic Airway Inflammation

The alarmin cytokine interleukin (IL)-33 plays an important proinflammatory role in type 2 immunity and can act on type 2 innate lymphoid cells (ILC2s) and type 2 T helper (T(H)2) cells in eosinophilic inflammation and asthma. The mechanistic target of rapamycin (mTOR) signaling pathway drives immun...

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Detalles Bibliográficos
Autores principales: Boberg, Emma, Weidner, Julie, Malmhäll, Carina, Calvén, Jenny, Corciulo, Carmen, Rådinger, Madeleine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9203889/
https://www.ncbi.nlm.nih.gov/pubmed/35720347
http://dx.doi.org/10.3389/fimmu.2022.915906

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9203889/
https://www.ncbi.nlm.nih.gov/pubmed/35720347
http://dx.doi.org/10.3389/fimmu.2022.915906

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