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Rapamycin Dampens Inflammatory Properties of Bone Marrow ILC2s in IL-33-Induced Eosinophilic Airway Inflammation
The alarmin cytokine interleukin (IL)-33 plays an important proinflammatory role in type 2 immunity and can act on type 2 innate lymphoid cells (ILC2s) and type 2 T helper (T(H)2) cells in eosinophilic inflammation and asthma. The mechanistic target of rapamycin (mTOR) signaling pathway drives immun...
Autores principales: | Boberg, Emma, Weidner, Julie, Malmhäll, Carina, Calvén, Jenny, Corciulo, Carmen, Rådinger, Madeleine |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9203889/ https://www.ncbi.nlm.nih.gov/pubmed/35720347 http://dx.doi.org/10.3389/fimmu.2022.915906 |
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