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Clinical presentation vs endoscopy for an early diagnosis of eosinophilic esophagitis: a case report

Eosinophilic esophagitis (EoE) is a type-2 mediated, chronic inflammatory disease showing an increase of both incidence and prevalence. Early diagnosis is mandatory, to prevent fibrostenotic complication of the disease. Due to the low sensitivity of the classic endoscopic features of the disease, a...

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Detalles Bibliográficos
Autores principales: Di Stefano, Michele, Grandi, Giacomo, Bonaso, Vera, Pagani, Elisabetta, Corazza, Gino Roberto, Di Sabatino, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Leibniz Research Centre for Working Environment and Human Factors 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9203986/
https://www.ncbi.nlm.nih.gov/pubmed/35721577
http://dx.doi.org/10.17179/excli2022-4838
Descripción
Sumario:Eosinophilic esophagitis (EoE) is a type-2 mediated, chronic inflammatory disease showing an increase of both incidence and prevalence. Early diagnosis is mandatory, to prevent fibrostenotic complication of the disease. Due to the low sensitivity of the classic endoscopic features of the disease, a strong clinical suspicion should drive the decision to collect mucosal biopsies of the esophagus. We describe the case of an atopic patient suffering from dysphagia with normal esophageal mucosa and frank histological hallmarks of the disease.