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Improving Control of Gene Therapy-Based Neurotrophin Delivery for Inner Ear Applications
Background: Survival and integrity of the spiral ganglion is vital for hearing in background noise and for optimal functioning of cochlear implants. Numerous studies have demonstrated that supplementation of supraphysiologic levels of the neurotrophins BDNF and NT-3 by pumps or gene therapy strategi...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9204055/ https://www.ncbi.nlm.nih.gov/pubmed/35721868 http://dx.doi.org/10.3389/fbioe.2022.892969 |