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Improving Control of Gene Therapy-Based Neurotrophin Delivery for Inner Ear Applications

Background: Survival and integrity of the spiral ganglion is vital for hearing in background noise and for optimal functioning of cochlear implants. Numerous studies have demonstrated that supplementation of supraphysiologic levels of the neurotrophins BDNF and NT-3 by pumps or gene therapy strategi...

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Detalles Bibliográficos
Autores principales:	St. Peter, Madeleine, Brough, Douglas E., Lawrence, Anna, Nelson-Brantley, Jennifer, Huang, Peixin, Harre, Jennifer, Warnecke, Athanasia, Staecker, Hinrich
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Bioengineering and Biotechnology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9204055/ https://www.ncbi.nlm.nih.gov/pubmed/35721868 http://dx.doi.org/10.3389/fbioe.2022.892969

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