Cargando…

Mangiferin Alleviates Postpartum Depression–Like Behaviors by Inhibiting MAPK Signaling in Microglia

Postpartum depression (PPD), a severe mental health disorder, is closely associated with decreased gonadal hormone levels during the postpartum period. Mangiferin (MGF) possesses a wide range of pharmacological activities, including anti-inflammation. Growing evidence has suggested that neuroinflamm...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yan, Meichen, Bo, Xuena, Zhang, Xinchao, Zhang, Jingdan, Liao, Yajin, Zhang, Haiyan, Cheng, Yong, Guo, Junxia, Cheng, Jinbo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9204178/ https://www.ncbi.nlm.nih.gov/pubmed/35721155 http://dx.doi.org/10.3389/fphar.2022.840567

Ejemplares similares

Deletion of Calhm2 alleviates MPTP-induced Parkinson's disease pathology by inhibiting EFHD2-STAT3 signaling in microglia
por: Bo, Xuena, et al.
Publicado: (2023)

Large Screening Identifies ACE2 Positively Correlates With NF-κB Signaling Activity and Targeting NF-κB Signaling Drugs Suppress ACE2 Levels
por: Yan, Meichen, et al.
Publicado: (2021)

Dlg1 Knockout Inhibits Microglial Activation and Alleviates Lipopolysaccharide-Induced Depression-Like Behavior in Mice
por: Peng, Zhixin, et al.
Publicado: (2021)

Dlg1 deletion in microglia ameliorates chronic restraint stress induced mice depression-like behavior
por: Li, Xiaoheng, et al.
Publicado: (2023)

Mangiferin promotes osteogenic differentiation and alleviates osteoporosis in the ovariectomized mouse via the AXL/ERK5 pathway
por: He, Jinwen, et al.
Publicado: (2022)

Hematopoietic Cell Kinase (HCK) Is Essential for NLRP3 Inflammasome Activation and Lipopolysaccharide-Induced Inflammatory Response In Vivo
por: Kong, Xiangxi, et al.
Publicado: (2020)

Mangiferin Ameliorates Hyperuricemic Nephropathy Which Is Associated With Downregulation of AQP2 and Increased Urinary Uric Acid Excretion
por: Li, Xuechen, et al.
Publicado: (2020)

The XPO1 Inhibitor KPT-8602 Ameliorates Parkinson’s Disease by Inhibiting the NF-κB/NLRP3 Pathway
por: Liu, Shuhan, et al.
Publicado: (2022)

Gestational Folic Acid Administration Alleviated Maternal Postpartum Emotional and Cognitive Dysfunction in Mice
por: Zhang, Qianyu, et al.
Publicado: (2021)

A monoamine oxidase B inhibitor ethyl ferulate suppresses microglia-mediated neuroinflammation and alleviates ischemic brain injury
por: Zou, Xinxin, et al.
Publicado: (2022)

Dapagliflozin alleviates myocardial ischemia/reperfusion injury by reducing ferroptosis via MAPK signaling inhibition
por: Chen, Weixiang, et al.
Publicado: (2023)

Modulation of gut microbiota alleviates cerebral ischemia/reperfusion injury in rats by inhibiting M1 polarization of microglia
por: Li, Hai-Jun, et al.
Publicado: (2023)

Apigenin Alleviates Autoimmune Uveitis by Inhibiting Microglia M1 Pro-Inflammatory Polarization
por: Shu, Nan, et al.
Publicado: (2023)

Neuroprotective potency of mangiferin against 3-nitropropionic acid induced Huntington’s disease-like symptoms in rats: possible antioxidant and anti-inflammatory mechanisms
por: Lum, Pei Teng, et al.
Publicado: (2023)

Mangiferin Improves Hepatic Lipid Metabolism Mainly Through Its Metabolite-Norathyriol by Modulating SIRT-1/AMPK/SREBP-1c Signaling
por: Li, Jian, et al.
Publicado: (2018)

Dapagliflozin alleviates renal fibrosis in a mouse model of adenine-induced renal injury by inhibiting TGF-β1/MAPK mediated mitochondrial damage
por: Zeng, Jianhua, et al.
Publicado: (2023)

Inflammatory pathophysiological mechanisms implicated in postpartum depression
por: Zhu, Jialei, et al.
Publicado: (2022)

Panax notoginseng Saponins Alleviate Coronary Artery Disease Through Hypermethylation of the miR-194-MAPK Pathway
por: Duan, Lian, et al.
Publicado: (2022)

Mangiferin Enhanced Autophagy via Inhibiting mTORC1 Pathway to Prevent High Glucose-Induced Cardiomyocyte Injury
por: Hou, Jun, et al.
Publicado: (2018)

Microglial deletion and inhibition alleviate behavior of post-traumatic stress disorder in mice
por: Li, Shuoshuo, et al.
Publicado: (2021)

Commentary: Targeting chemoattractant chemokine (C–C motif) ligand 2 derived from astrocytes is a promising therapeutic approach in the treatment of neuromyelitis optica spectrum disorders
por: Zhang, Jingdan, et al.
Publicado: (2023)

Comparative efficacy and acceptability of pharmacotherapies for postpartum depression: A systematic review and network meta-analysis
por: Zhang, Qing, et al.
Publicado: (2022)

Anti-allodynic Effect of Mangiferin in Rats With Chronic Post-ischemia Pain: A Model of Complex Regional Pain Syndrome Type I
por: Garrido-Suárez, Bárbara B., et al.
Publicado: (2018)

Mangiferin Relieves Lipopolysaccharide-Induced Injury by Up-Regulating miR-181a via Targeting PTEN in ATDC5 Cells
por: Ma, Yunfei, et al.
Publicado: (2020)

Study of the interaction between self-assembling peptide and mangiferin and in vitro release of mangiferin from in situ hydrogel
por: Meng, Cui, et al.
Publicado: (2019)

Impairment of Mitochondrial Biogenesis and Dynamics Involved in Isoniazid-Induced Apoptosis of HepG2 Cells Was Alleviated by p38 MAPK Pathway
por: Zhang, Tianguang, et al.
Publicado: (2017)

Tamarixinin A Alleviates Joint Destruction of Rheumatoid Arthritis by Blockade of MAPK and NF-κB Activation
por: Zhuang, Yuanyuan, et al.
Publicado: (2017)

Antiproliferative, Antiangiogenic, and Antimetastatic Therapy Response by Mangiferin in a Syngeneic Immunocompetent Colorectal Cancer Mouse Model Involves Changes in Mitochondrial Energy Metabolism
por: Rodriguez-Gonzalez, Julio César, et al.
Publicado: (2021)

Mib2 Deficiency Inhibits Microglial Activation and Alleviates Ischemia-Induced Brain Injury
por: Li, Xiaoheng, et al.
Publicado: (2020)

Venlafaxine Improves the Cognitive Impairment and Depression-Like Behaviors in a Cuprizone Mouse Model by Alleviating Demyelination and Neuroinflammation in the Brain
por: Zhang, Yanbo, et al.
Publicado: (2019)

Co-Treatment With Verapamil and Curcumin Attenuates the Behavioral Alterations Observed in Williams–Beuren Syndrome Mice by Regulation of MAPK Pathway and Microglia Overexpression
por: Ortiz-Romero, Paula, et al.
Publicado: (2021)

Barbiturates and pyrazolopyridines for the treatment of postpartum depression—repurposing of two drug classes
por: Horwitz, Alexander B., et al.
Publicado: (2023)

Screening, Characterization and Evaluation of Mangiferin Polymorphs
por: Yang, Shiying, et al.
Publicado: (2020)

Mangiferin relieves CCl4-induced liver fibrosis in mice
por: Zhang, Lijun, et al.
Publicado: (2023)

Inhibition of Autophagy in Microglia Alters Depressive-Like Behavior via BDNF Pathway in Postpartum Depression
por: Tan, Xiaoning, et al.
Publicado: (2018)

Gypenoside L and Gypenoside LI Inhibit Proliferation in Renal Cell Carcinoma via Regulation of the MAPK and Arachidonic Acid Metabolism Pathways
por: Liu, Hui, et al.
Publicado: (2022)

Krill Oil Alleviated Methamphetamine-Induced Memory Impairment via the MAPK Signaling Pathway and Dopaminergic Synapse Pathway
por: Ru, Qin, et al.
Publicado: (2021)

Rice bran derivatives alleviate microglia activation: possible involvement of MAPK pathway
por: Bhatia, Harsharan S., et al.
Publicado: (2016)

Mangiferin Ameliorates Cisplatin Induced Acute Kidney Injury by Upregulating Nrf-2 via the Activation of PI3K and Exhibits Synergistic Anticancer Activity With Cisplatin
por: Sadhukhan, Pritam, et al.
Publicado: (2018)

Cinnamomum cassia (L.) J.Presl Alleviates Allergic Responses in Asthmatic Mice via Suppression of MAPKs and MMP-9
por: Lim, Je-Oh, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_barcv7hcomvprvdpbjrqo7qb45