DRD2 Agonist Cabergoline Abolished the Escape Mechanism Induced by mTOR Inhibitor Everolimus in Tumoral Pituitary Cells

The mammalian target of rapamycin (mTOR) inhibitor everolimus has been shown to display antiproliferative effects on a wide spectrum of tumors. In vitro studies demonstrated that everolimus inhibited pituitary neuroendocrine tumor (PitNET) cell growth in a subset of patients. Sensitivity to everolim...

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Detalles Bibliográficos
Autores principales: Mangili, Federica, Esposito, Emanuela, Treppiedi, Donatella, Catalano, Rosa, Marra, Giusy, Di Muro, Genesio, Barbieri, Anna Maria, Locatelli, Marco, Lania, Andrea G., Mangone, Alessandra, Spada, Anna, Arosio, Maura, Peverelli, Erika, Mantovani, Giovanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9204243/
https://www.ncbi.nlm.nih.gov/pubmed/35721701
http://dx.doi.org/10.3389/fendo.2022.867822

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