Cargando…

Pathologic Inflammation in Malnutrition Is Driven by Proinflammatory Intestinal Microbiota, Large Intestine Barrier Dysfunction, and Translocation of Bacterial Lipopolysaccharide

Acute malnutrition, or wasting, is implicated in over half of all deaths in children under five and increases risk of infectious disease. Studies in humans and preclinical models have demonstrated that malnutrition is linked to an immature intestinal microbiota characterized by increased prevalence...

Descripción completa

Detalles Bibliográficos
Autores principales:	Patterson, Grace T., Osorio, Elvia Y., Peniche, Alex, Dann, Sara M., Cordova, Erika, Preidis, Geoffrey A., Suh, Ji Ho, Ito, Ichiaki, Saldarriaga, Omar A., Loeffelholz, Michael, Ajami, Nadim J., Travi, Bruno L., Melby, Peter C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9204284/ https://www.ncbi.nlm.nih.gov/pubmed/35720380 http://dx.doi.org/10.3389/fimmu.2022.846155

Ejemplares similares

Malnutrition-related parasite dissemination from the skin in visceral leishmaniasis is driven by PGE(2)-mediated amplification of CCR7-related trafficking of infected inflammatory monocytes
por: Osorio, E. Yaneth, et al.
Publicado: (2023)

Efficacy of histamine H1 receptor antagonists azelastine and fexofenadine against cutaneous Leishmania major infection
por: Peniche, Alex G., et al.
Publicado: (2020)

The Malnutrition-Related Increase in Early Visceralization of Leishmania donovani Is Associated with a Reduced Number of Lymph Node Phagocytes and Altered Conduit System Flow
por: Ibrahim, Marwa K., et al.
Publicado: (2013)

Splenic CD4(+) T Cells in Progressive Visceral Leishmaniasis Show a Mixed Effector-Regulatory Phenotype and Impair Macrophage Effector Function through Inhibitory Receptor Expression
por: Medina-Colorado, Audrie A., et al.
Publicado: (2017)

Identification of Small Molecule Lead Compounds for Visceral Leishmaniasis Using a Novel Ex Vivo Splenic Explant Model System
por: Osorio, Yaneth, et al.
Publicado: (2011)

Gelatin tannate reduces the proinflammatory effects of lipopolysaccharide in human intestinal epithelial cells
por: Frasca, Giuseppina, et al.
Publicado: (2012)

A secondary wave of neutrophil infiltration causes necrosis and ulceration in lesions of experimental American cutaneous leishmaniasis
por: Peniche, Alex G., et al.
Publicado: (2017)

Krüppel-like factor 5 is an important mediator for lipopolysaccharide-induced proinflammatory response in intestinal epithelial cells
por: Chanchevalap, Sengthong, et al.
Publicado: (2006)

Molecular proinflammatory mechanism in the intestinal muscularis following intestinal manipulation
por: Kalff, JC, et al.
Publicado: (2001)

Inflammatory stimuli alter bone marrow composition and compromise bone health in the malnourished host
por: Osorio, E. Yaneth, et al.
Publicado: (2022)

Growth Factor and Th2 Cytokine Signaling Pathways Converge at STAT6 to Promote Arginase Expression in Progressive Experimental Visceral Leishmaniasis
por: Osorio, E. Yaneth, et al.
Publicado: (2014)

Transcriptional Profiling in Experimental Visceral Leishmaniasis Reveals a Broad Splenic Inflammatory Environment that Conditions Macrophages toward a Disease-Promoting Phenotype
por: Kong, Fanping, et al.
Publicado: (2017)

Progressive Visceral Leishmaniasis Is Driven by Dominant Parasite-induced STAT6 Activation and STAT6-dependent Host Arginase 1 Expression
por: Osorio, E. Yaneth, et al.
Publicado: (2012)

Duplex real-time reverse transcriptase PCR to determine cytokine mRNA expression in a hamster model of New World cutaneous leishmaniasis
por: Espitia, Claudia M, et al.
Publicado: (2010)

Dietary Ganglioside Reduces Proinflammatory Signaling in the Intestine
por: Miklavcic, John Janez, et al.
Publicado: (2012)

Environmental, Metabolic, and Inflammatory Factors Converge in the Pathogenesis of Moderate Acute Malnutrition in Children: An Observational Cohort Study
por: Patterson, Grace T., et al.
Publicado: (2021)

CFTR Knockdown induces proinflammatory changes in intestinal epithelial cells
por: Crites, Karoline St-Martin, et al.
Publicado: (2015)

Impact of childhood malnutrition and intestinal microbiota on MDR infections
por: Holowka, Thomas, et al.
Publicado: (2023)

Intestinal Cell Kinase Is a Novel Participant in Intestinal Cell Signaling Responses to Protein Malnutrition
por: Bolick, David T., et al.
Publicado: (2014)

In-situ proliferation contributes to the accumulation of myeloid cells in the spleen during progressive experimental visceral leishmaniasis
por: Osorio, E. Yaneth, et al.
Publicado: (2020)

Berberine Decreases Intestinal GLUT2 Translocation and Reduces Intestinal Glucose Absorption in Mice
por: Zhang, Min, et al.
Publicado: (2021)

Intrauterine Malnutrition Reduced Long Leptin Receptor Isoform Expression and Proinflammatory Cytokine Production in Male Rat Pulmonary Endothelial Cells Stimulated by Lipopolysaccharide
por: Balbino, Aleksandro M., et al.
Publicado: (2018)

Proinflammatory Liver and Antiinflammatory Intestinal Mediators Involved in Portal Hypertensive Rats
por: Aller, Maria Angeles, et al.
Publicado: (2005)

Interactions between intestinal pathogens, enteropathy and malnutrition in developing countries
por: Prendergast, Andrew J., et al.
Publicado: (2016)

Intestinal disturbances associated with mortality of children with complicated severe malnutrition
por: Wen, Bijun, et al.
Publicado: (2023)

Intestinal Barrier Dysfunction, LPS Translocation, and Disease Development
por: Ghosh, Siddhartha S, et al.
Publicado: (2020)

Trafficking of Shigella Lipopolysaccharide in Polarized Intestinal Epithelial Cells
por: Beatty, Wandy L., et al.
Publicado: (1999)

N-acetylcysteine modulates lipopolysaccharide-induced intestinal dysfunction
por: Lee, Sang In, et al.
Publicado: (2019)

Delineating proinflammatory microenvironmental signals by ex vivo modeling of the immature intestinal stroma
por: Ichinose, Mari, et al.
Publicado: (2021)

Markers of malnutrition after intestinal transplantation: the role of IGF-1 and calprotectin
por: Vrakas, Georgios, et al.
Publicado: (2015)

Transcriptional profiling of the spleen in progressive visceral leishmaniasis reveals mixed expression of type 1 and type 2 cytokine-responsive genes
por: Espitia, Claudia M, et al.
Publicado: (2014)

Schistosoma mansoni infection is associated with quantitative and qualitative modifications of the mammalian intestinal microbiota
por: Jenkins, Timothy P., et al.
Publicado: (2018)

Dietary Fiber Ameliorates Lipopolysaccharide-Induced Intestinal Barrier Function Damage in Piglets by Modulation of Intestinal Microbiome
por: Sun, Xiao, et al.
Publicado: (2021)

Iron-deficiency anemia increases intestinal bacterial translocation in rats
por: Morais, MB, et al.
Publicado: (2005)

Intestinal Bacteria Composition and Translocation of Bacteria in Inflammatory Bowel Disease
por: Vrakas, Spyros, et al.
Publicado: (2017)

Low potassium disrupt intestinal barrier and result in bacterial translocation
por: Wu, Haishan, et al.
Publicado: (2022)

HIV induces production of IL-18 from intestinal epithelial cells that increases intestinal permeability and microbial translocation
por: Allam, Ossama, et al.
Publicado: (2018)

Effect of zinc supplementation on growth performance, intestinal development, and intestinal barrier function in Pekin ducks with lipopolysaccharide challenge
por: Xie, Yueqin, et al.
Publicado: (2021)

ACE2 links amino acid malnutrition to microbial ecology and intestinal inflammation
por: Hashimoto, Tatsuo, et al.
Publicado: (2012)

From intestinal colonization to systemic infections: Candida albicans translocation and dissemination
por: Sprague, Jakob L., et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_i7pafmdmr0ltsh3u6l8hb41f4s