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Anaplasma phagocytophilum Ankyrin A Protein (AnkA) Enters the Nucleus Using an Importin-β-, RanGTP-Dependent Mechanism

Anaplasma phagocytophilum, a tick-borne obligately intracellular bacterium of neutrophils, causes human granulocytic anaplasmosis. Ankyrin A (AnkA), an effector protein with multiple ankyrin repeats (AR) is injected via type IV-secretion into the host neutrophil to gain access to the nucleus where i...

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Detalles Bibliográficos
Autores principales:	Kim, Yuri, Wang, Jianyang, Clemens, Emily G., Grab, Dennis J., Dumler, J. Stephen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Cellular and Infection Microbiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9204287/ https://www.ncbi.nlm.nih.gov/pubmed/35719343 http://dx.doi.org/10.3389/fcimb.2022.828605

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