Modification of Extracellular Matrix by the Product of DHA Oxidation Switches Macrophage Adhesion Patterns and Promotes Retention of Macrophages During Chronic Inflammation

Oxidation of polyunsaturated fatty acids contributes to different aspects of the inflammatory response due to the variety of products generated. Specifically, the oxidation of DHA produces the end-product, carboxyethylpyrrole (CEP), which forms a covalent adduct with proteins via an ϵ-amino group of...

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Detalles Bibliográficos
Autores principales: Casteel, Jared L., Keever, Kasey R., Ardell, Christopher L., Williams, David L., Gao, Detao, Podrez, Eugene A., Byzova, Tatiana V., Yakubenko, Valentin P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9204313/
https://www.ncbi.nlm.nih.gov/pubmed/35720381
http://dx.doi.org/10.3389/fimmu.2022.867082

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