Low Levels of Factor H Family Proteins During Meningococcal Disease Indicate Systemic Processes Rather Than Specific Depletion by Neisseria meningitidis

Neisseria meningitidis, the causative agent of meningococcal disease (MD), evades complement-mediated clearance upon infection by ‘hijacking’ the human complement regulator factor H (FH). The FH protein family also comprises the homologous FH-related (FHR) proteins, hypothesized to act as antagonist...

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Detalles Bibliográficos
Autores principales: van Beek, Anna E., Pouw, Richard B., Wright, Victoria J., Sallah, Neneh, Inwald, David, Hoggart, Clive, Brouwer, Mieke C., Galassini, Rachel, Thomas, John, Calvo-Bado, Leo, Fink, Colin G., Jongerius, Ilse, Hibberd, Martin, Wouters, Diana, Levin, Michael, Kuijpers, Taco W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9204383/
https://www.ncbi.nlm.nih.gov/pubmed/35720329
http://dx.doi.org/10.3389/fimmu.2022.876776

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9204383/
https://www.ncbi.nlm.nih.gov/pubmed/35720329
http://dx.doi.org/10.3389/fimmu.2022.876776

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