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Intratumoral delivery of dendritic cells plus anti-HER2 therapy triggers both robust systemic antitumor immunity and complete regression in HER2 mammary carcinoma
BACKGROUND: Human epidermal growth factor receptor 2 (HER2) targeted antibodies in combination with chemotherapy has improved outcomes of HER2 positive (pos) breast cancer (BC) but toxicity of therapy remains a problem. High levels of tumor-infiltrating lymphocytes are associated with increased path...
Autores principales: | Ramamoorthi, Ganesan, Kodumudi, Krithika, Snyder, Colin, Grover, Payal, Zhang, Hongtao, Greene, Mark I, Basu, Amrita, Gallen, Corey, Wiener, Doris, Costa, Ricardo L B, Han, Hyo S, Koski, Gary, Czerniecki, Brian J |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9204433/ https://www.ncbi.nlm.nih.gov/pubmed/35710296 http://dx.doi.org/10.1136/jitc-2022-004841 |
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