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Synthetic oxepanoprolinamide iboxamycin is active against Listeria monocytogenes despite the intrinsic resistance mediated by VgaL/Lmo0919 ABCF ATPase

BACKGROUND: Listeriosis is a food-borne disease caused by the Gram-positive Bacillota (Firmicute) bacterium Listeria monocytogenes. Clinical L. monocytogenes isolates are often resistant to clinically used lincosamide clindamycin, thus excluding clindamycin as a viable treatment option. OBJECTIVES:...

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Detalles Bibliográficos
Autores principales: Brodiazhenko, Tetiana, Turnbull, Kathryn Jane, Wu, Kelvin J Y, Takada, Hiraku, Tresco, Ben I C, Tenson, Tanel, Myers, Andrew G, Hauryliuk, Vasili
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9204466/
https://www.ncbi.nlm.nih.gov/pubmed/35733912
http://dx.doi.org/10.1093/jacamr/dlac061