Comparative Immunogenicity of Bacterially Expressed Soluble Trimers and Nanoparticle Displayed Influenza Hemagglutinin Stem Immunogens

Current influenza vaccines need to be updated annually due to mutations in the globular head of the viral surface protein, hemagglutinin (HA). To address this, vaccine candidates have been designed based on the relatively conserved HA stem domain and have shown protective efficacy in animal models....

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Detalles Bibliográficos
Autores principales: Kar, Uddipan, Khaleeq, Sara, Garg, Priyanka, Bhat, Madhuraj, Reddy, Poorvi, Vignesh, Venkada Subramanian, Upadhyaya, Aditya, Das, Mili, Chakshusmathi, Ghadiyaram, Pandey, Suman, Dutta, Somnath, Varadarajan, Raghavan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9204493/
https://www.ncbi.nlm.nih.gov/pubmed/35720346
http://dx.doi.org/10.3389/fimmu.2022.890622

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