Possible association between Guillain-Barré syndrome and SARS-CoV-2 infection in children: A case report and literature review

Neurological manifestations of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection have been reported in adults and in children, varying from mild to more debilitant symptoms, including fatigue, headache and dizziness. A series of studies have revealed a possible association betwe...

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Detalles Bibliográficos
Autores principales: Mussinatto, Ilaria, Benevenuta, Chiara, Caci, Anna, Calvo, Mario M., Impastato, Maria, Barra, Massimo, Genovese, Egidio, Timeus, Fabio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2022
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9204538/
https://www.ncbi.nlm.nih.gov/pubmed/35747147
http://dx.doi.org/10.3892/etm.2022.11389
Descripción
Sumario:Neurological manifestations of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection have been reported in adults and in children, varying from mild to more debilitant symptoms, including fatigue, headache and dizziness. A series of studies have revealed a possible association between Guillain-Barré syndrome (GBS), the most common cause of acute flaccid paralysis at all ages, and SARS-CoV-2 infection. Case reports of novel coronavirus disease 2019 (COVID-19)-associated GBS mainly include adult patients, while only a few pediatric cases have been reported. The present study describes a case of GBS in an Italian 9-year-old girl with previous SARS-CoV-2 infection as a possible trigger, and also conducts a literature review on pediatric COVID-19-associated GBS cases.

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