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Distinct actin–tropomyosin cofilament populations drive the functional diversification of cytoskeletal myosin motor complexes

The effects of N-terminal acetylation of the high molecular weight tropomyosin isoforms Tpm1.6 and Tpm2.1 and the low molecular weight isoforms Tpm1.12, Tpm3.1, and Tpm4.2 on the actin affinity and the thermal stability of actin-tropomyosin cofilaments are described. Furthermore, we show how the exc...

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Detalles Bibliográficos
Autores principales:	Reindl, Theresia, Giese, Sven, Greve, Johannes N., Reinke, Patrick Y., Chizhov, Igor, Latham, Sharissa L., Mulvihill, Daniel P., Taft, Manuel H., Manstein, Dietmar J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9204724/ https://www.ncbi.nlm.nih.gov/pubmed/35720262 http://dx.doi.org/10.1016/j.isci.2022.104484

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