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Prior Signal Acquisition Software Versions for Orbitrap Underestimate Low Isobaric Mass Tag Intensities, Without Detriment to Differential Abundance Experiments

[Image: see text] Tandem mass tags (TMTs) enable simple and accurate quantitative proteomics for multiplexed samples by relative quantification of tag reporter ions. Orbitrap quantification of reporter ions has been associated with a characteristic notch region in intensity distribution, within whic...

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Detalles Bibliográficos
Autores principales:	Smith, Tom S., Andrejeva, Anna, Christopher, Josie, Crook, Oliver M., Elzek, Mohamed, Lilley, Kathryn S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2022
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9204819/ https://www.ncbi.nlm.nih.gov/pubmed/35726249 http://dx.doi.org/10.1021/acsmeasuresciau.1c00053

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