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Insulin-inducible THRSP maintains mitochondrial function and regulates sphingolipid metabolism in human adipocytes

BACKGROUND: Thyroid hormone responsive protein (THRSP) is a lipogenic nuclear protein that is highly expressed in murine adipose tissue, but its role in humans remains unknown. METHODS: We characterized the insulin regulation of THRSP in vivo in human adipose tissue biopsies and in vitro in Simpson-...

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Detalles Bibliográficos
Autores principales:	Ahonen, Maria A., Höring, Marcus, Nguyen, Van Dien, Qadri, Sami, Taskinen, Juuso H., Nagaraj, Meghana, Wabitsch, Martin, Fischer-Posovszky, Pamela, Zhou, You, Liebisch, Gerhard, Haridas, P. A. Nidhina, Yki-Järvinen, Hannele, Olkkonen, Vesa M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9204892/ https://www.ncbi.nlm.nih.gov/pubmed/35715726 http://dx.doi.org/10.1186/s10020-022-00496-3

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