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Andexanet alfa versus four-factor prothrombin complex concentrate for the reversal of apixaban- or rivaroxaban-associated intracranial hemorrhage: a propensity score-overlap weighted analysis

BACKGROUND: Andexanet alfa is approved (FDA “accelerated approval”; EMA “conditional approval”) as the first specific reversal agent for factor Xa (FXa) inhibitor-associated uncontrolled or life-threatening bleeding. Four-factor prothrombin complex concentrates (4F-PCC) are commonly used as an off-l...

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Detalles Bibliográficos
Autores principales:	Costa, Olivia S., Connolly, Stuart J., Sharma, Mukul, Beyer-Westendorf, Jan, Christoph, Mary J., Lovelace, Belinda, Coleman, Craig I.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9204964/ https://www.ncbi.nlm.nih.gov/pubmed/35710578 http://dx.doi.org/10.1186/s13054-022-04043-8

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