Tumor-associated macrophages promote epithelial–mesenchymal transition and the cancer stem cell properties in triple-negative breast cancer through CCL2/AKT/β-catenin signaling

BACKGROUND: Triple-negative breast cancer (TNBC) is a highly aggressive subtype of breast cancer with poor prognosis and limited treatment. As a major component of the tumor microenvironment, tumor-associated macrophages (TAMs) play an important role in facilitating the aggressive behavior of TNBC....

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Detalles Bibliográficos
Autores principales: Chen, Xiangzhou, Yang, Mingqiang, Yin, Jiang, Li, Pan, Zeng, Shanshan, Zheng, Guopei, He, Zhimin, Liu, Hao, Wang, Qian, Zhang, Fan, Chen, Danyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9205034/
https://www.ncbi.nlm.nih.gov/pubmed/35715860
http://dx.doi.org/10.1186/s12964-022-00888-2

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