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IL-1R/C3aR signaling regulates synaptic pruning in the prefrontal cortex of depression
BACKGROUND: Major depressive disorder is characterized by not only monoamine neurotransmitters deficiencies but also persistent neuroinflammation. The complement system is an attractive therapeutic target for various inflammation-related diseases due to its early activation in inflammatory processes...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9205119/ https://www.ncbi.nlm.nih.gov/pubmed/35715851 http://dx.doi.org/10.1186/s13578-022-00832-4 |