Human umbilical cord-derived mesenchymal stem cells not only ameliorate blood glucose but also protect vascular endothelium from diabetic damage through a paracrine mechanism mediated by MAPK/ERK signaling

BACKGROUND: Endothelial damage is an initial step of macro- and micro-vasculature dysfunctions in diabetic patients, accounting for a high incidence of diabetic vascular complications, such as atherosclerosis, nephropathy, retinopathy, and neuropathy. However, clinic lacks effective therapeutics tar...

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Detalles Bibliográficos
Autores principales: Liu, Yi, Chen, Jingan, Liang, Haowei, Cai, Yueqin, Li, Xinyue, Yan, Li, Zhou, Li, Shan, Letian, Wang, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9205155/
https://www.ncbi.nlm.nih.gov/pubmed/35715841
http://dx.doi.org/10.1186/s13287-022-02927-8

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