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Granulocyte-Macrophage Colony-Stimulating Factor Modulates Myeloid-Derived Suppressor Cells and Treg Activity in Decompensated Cirrhotic Patients With Sepsis
BACKGROUND: Decompensated cirrhosis patients are more prone to bacterial infections. Myeloid-derived suppressor cells (MDSCs) expand in sepsis patients and disrupt immune cell functions. Granulocyte-macrophage colony-stimulating factor (GM-CSF) therapy helps in restoring immune cell functions and re...
Autores principales: | Sehgal, Rashi, Maiwall, Rakhi, Rajan, Vijayaraghavan, Islam, Mojahidul, Baweja, Sukriti, Kaur, Navkiran, Kumar, Guresh, Ramakrishna, Gayatri, Sarin, Shiv K., Trehanpati, Nirupma |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9205181/ https://www.ncbi.nlm.nih.gov/pubmed/35720398 http://dx.doi.org/10.3389/fimmu.2022.828949 |
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