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Granulocyte-Macrophage Colony-Stimulating Factor Modulates Myeloid-Derived Suppressor Cells and Treg Activity in Decompensated Cirrhotic Patients With Sepsis

BACKGROUND: Decompensated cirrhosis patients are more prone to bacterial infections. Myeloid-derived suppressor cells (MDSCs) expand in sepsis patients and disrupt immune cell functions. Granulocyte-macrophage colony-stimulating factor (GM-CSF) therapy helps in restoring immune cell functions and re...

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Detalles Bibliográficos
Autores principales: Sehgal, Rashi, Maiwall, Rakhi, Rajan, Vijayaraghavan, Islam, Mojahidul, Baweja, Sukriti, Kaur, Navkiran, Kumar, Guresh, Ramakrishna, Gayatri, Sarin, Shiv K., Trehanpati, Nirupma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9205181/
https://www.ncbi.nlm.nih.gov/pubmed/35720398
http://dx.doi.org/10.3389/fimmu.2022.828949

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