Monitoring occurrence of SARS-CoV-2 in school populations: A wastewater-based approach

Clinical testing of children in schools is challenging, with economic implications limiting its frequent use as a monitoring tool of the risks assumed by children and staff during the COVID-19 pandemic. Here, a wastewater-based epidemiology approach has been used to monitor 16 schools (10 primary, 5...

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Detalles Bibliográficos
Autores principales: Castro-Gutierrez, Victor, Hassard, Francis, Vu, Milan, Leitao, Rodrigo, Burczynska, Beata, Wildeboer, Dirk, Stanton, Isobel, Rahimzadeh, Shadi, Baio, Gianluca, Garelick, Hemda, Hofman, Jan, Kasprzyk-Hordern, Barbara, Kwiatkowska, Rachel, Majeed, Azeem, Priest, Sally, Grimsley, Jasmine, Lundy, Lian, Singer, Andrew C., Di Cesare, Mariachiara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9205509/
https://www.ncbi.nlm.nih.gov/pubmed/35714109
http://dx.doi.org/10.1371/journal.pone.0270168
Descripción
Sumario:Clinical testing of children in schools is challenging, with economic implications limiting its frequent use as a monitoring tool of the risks assumed by children and staff during the COVID-19 pandemic. Here, a wastewater-based epidemiology approach has been used to monitor 16 schools (10 primary, 5 secondary and 1 post-16 and further education) in England. A total of 296 samples over 9 weeks have been analysed for N1 and E genes using qPCR methods. Of the samples returned, 47.3% were positive for one or both genes with a detection frequency in line with the respective local community. WBE offers a low cost, non-invasive approach for supplementing clinical testing and can provide longitudinal insights that are impractical with traditional clinical testing.

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