Structure of the rabies virus glycoprotein trimer bound to a prefusion-specific neutralizing antibody

Rabies infection is nearly 100% lethal if untreated and kills more than 50,000 people annually, many of them children. Existing rabies vaccines target the rabies virus glycoprotein (RABV-G) but generate short-lived immune responses, likely because the protein is heterogeneous under physiological con...

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Detalles Bibliográficos
Autores principales: Callaway, Heather M., Zyla, Dawid, Larrous, Florence, de Melo, Guilherme Dias, Hastie, Kathryn M., Avalos, Ruben Diaz, Agarwal, Alyssa, Corti, Davide, Bourhy, Hervé, Saphire, Erica Ollmann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9205594/
https://www.ncbi.nlm.nih.gov/pubmed/35714192
http://dx.doi.org/10.1126/sciadv.abp9151

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