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Female reproductive life span is extended by targeted removal of fibrotic collagen from the mouse ovary
The female ovary contains a finite number of oocytes, and their release at ovulation becomes sporadic and disordered with aging and with obesity, leading to loss of fertility. Understanding the molecular defects underpinning this pathology is essential as age of childbearing and obesity rates increa...
Autores principales: | Umehara, Takashi, Winstanley, Yasmyn E., Andreas, Eryk, Morimoto, Atsushi, Williams, Elisha J., Smith, Kirsten M., Carroll, John, Febbraio, Mark A., Shimada, Masayuki, Russell, Darryl L., Robker, Rebecca L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9205599/ https://www.ncbi.nlm.nih.gov/pubmed/35714185 http://dx.doi.org/10.1126/sciadv.abn4564 |
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