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Relationship Between a Vitamin D Genetic Risk Score and Autoantibodies Among First-Degree Relatives of Probands With Rheumatoid Arthritis and Systemic Lupus Erythematosus

OBJECTIVE: Higher 25-hydroxyvitamin D (25(OH)D) levels have been associated with reduced risk for autoimmune diseases and are influenced by vitamin D metabolism genes. We estimated genetically-determined vitamin D levels by calculating a genetic risk score (GRS) and investigated whether the vitamin...

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Detalles Bibliográficos
Autores principales:	Vanderlinden, Lauren A., Bemis, Elizabeth A., Seifert, Jennifer, Guthridge, Joel M., Young, Kendra A., Demoruelle, Mary Kristen, Feser, Marie, DeJager, Wade, Macwana, Susan, Mikuls, Ted R., O’Dell, James R., Weisman, Michael H., Buckner, Jane, Keating, Richard M., Gaffney, Patrick M., Kelly, Jennifer A., Langefeld, Carl D., Deane, Kevin D., James, Judith A., Holers, Vernon Michael, Norris, Jill M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9205604/ https://www.ncbi.nlm.nih.gov/pubmed/35720397 http://dx.doi.org/10.3389/fimmu.2022.881332

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