In utero origin of myelofibrosis presenting in adult monozygotic twins

The latency between acquisition of an initiating somatic driver mutation by a single-cell and clinical presentation with cancer is largely unknown. We describe a remarkable case of monozygotic twins presenting with CALR mutation-positive myeloproliferative neoplasms (MPNs) (aged 37 and 38 years), wi...

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Detalles Bibliográficos
Autores principales: Sousos, Nikolaos, Ní Leathlobhair, Máire, Simoglou Karali, Christina, Louka, Eleni, Bienz, Nicola, Royston, Daniel, Clark, Sally-Ann, Hamblin, Angela, Howard, Kieran, Mathews, Vikram, George, Biju, Roy, Anindita, Psaila, Bethan, Wedge, David C., Mead, Adam J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9205768/
https://www.ncbi.nlm.nih.gov/pubmed/35637336
http://dx.doi.org/10.1038/s41591-022-01793-4

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