Adipocyte-derived kynurenine promotes obesity and insulin resistance by activating the AhR/STAT3/IL-6 signaling

Aberrant amino acid metabolism is a common event in obesity. Particularly, subjects with obesity are characterized by the excessive plasma kynurenine (Kyn). However, the primary source of Kyn and its impact on metabolic syndrome are yet to be fully addressed. Herein, we show that the overexpressed i...

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Detalles Bibliográficos
Autores principales: Huang, Teng, Song, Jia, Gao, Jia, Cheng, Jia, Xie, Hao, Zhang, Lu, Wang, Yu-Han, Gao, Zhichao, Wang, Yi, Wang, Xiaohui, He, Jinhan, Liu, Shiwei, Yu, Qilin, Zhang, Shu, Xiong, Fei, Zhou, Qing, Wang, Cong-Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9205899/
https://www.ncbi.nlm.nih.gov/pubmed/35715443
http://dx.doi.org/10.1038/s41467-022-31126-5

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