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Impact of continuity of care on risk for major osteoporotic fracture in patients with new onset rheumatoid arthritis
There is a clear relationship between rheumatoid arthritis (RA) and major osteoporotic fracture (MOF), although there is limited evidence on the effect of continuity of care (COC) on MOF in these patients. We investigated the association between COC and risk of MOF, including fractures of the lumbar...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9205920/ https://www.ncbi.nlm.nih.gov/pubmed/35715560 http://dx.doi.org/10.1038/s41598-022-14368-7 |
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author | Kim, Seung Hoon Kim, Hyunkyu Jeong, Sung Hoon Jang, Suk-Yong Park, Eun-Cheol |
author_facet | Kim, Seung Hoon Kim, Hyunkyu Jeong, Sung Hoon Jang, Suk-Yong Park, Eun-Cheol |
author_sort | Kim, Seung Hoon |
collection | PubMed |
description | There is a clear relationship between rheumatoid arthritis (RA) and major osteoporotic fracture (MOF), although there is limited evidence on the effect of continuity of care (COC) on MOF in these patients. We investigated the association between COC and risk of MOF, including fractures of the lumbar spine and pelvis, forearm, and hip, among newly diagnosed RA patients aged ≥ 60 years. A total of 8715 incident RA patients from 2004 to 2010 were included from the Korean National Health Insurance Service-Senior cohort database. Participants were categorized into a good and bad COC group according to the COC index. The cumulative incidence of MOF was higher in RA patients with bad than in those with good COC (p < 0.001). The incidence rates of MOF were 4439 and 3275 cases per 100,000 person-years in patients with bad and good COC, respectively. RA patients with bad COC had an increased incidence of overall MOF (adjusted hazard ratio, 1.32; 95% confidence interval, 1.14–1.53), with the highest increase in risk being that of forearm fracture. An increased MOF risk in patients with bad COC was predominantly observed in females. This study suggested that interventions that can improve COC in patients with RA should be considered. |
format | Online Article Text |
id | pubmed-9205920 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-92059202022-06-19 Impact of continuity of care on risk for major osteoporotic fracture in patients with new onset rheumatoid arthritis Kim, Seung Hoon Kim, Hyunkyu Jeong, Sung Hoon Jang, Suk-Yong Park, Eun-Cheol Sci Rep Article There is a clear relationship between rheumatoid arthritis (RA) and major osteoporotic fracture (MOF), although there is limited evidence on the effect of continuity of care (COC) on MOF in these patients. We investigated the association between COC and risk of MOF, including fractures of the lumbar spine and pelvis, forearm, and hip, among newly diagnosed RA patients aged ≥ 60 years. A total of 8715 incident RA patients from 2004 to 2010 were included from the Korean National Health Insurance Service-Senior cohort database. Participants were categorized into a good and bad COC group according to the COC index. The cumulative incidence of MOF was higher in RA patients with bad than in those with good COC (p < 0.001). The incidence rates of MOF were 4439 and 3275 cases per 100,000 person-years in patients with bad and good COC, respectively. RA patients with bad COC had an increased incidence of overall MOF (adjusted hazard ratio, 1.32; 95% confidence interval, 1.14–1.53), with the highest increase in risk being that of forearm fracture. An increased MOF risk in patients with bad COC was predominantly observed in females. This study suggested that interventions that can improve COC in patients with RA should be considered. Nature Publishing Group UK 2022-06-17 /pmc/articles/PMC9205920/ /pubmed/35715560 http://dx.doi.org/10.1038/s41598-022-14368-7 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Article Kim, Seung Hoon Kim, Hyunkyu Jeong, Sung Hoon Jang, Suk-Yong Park, Eun-Cheol Impact of continuity of care on risk for major osteoporotic fracture in patients with new onset rheumatoid arthritis |
title | Impact of continuity of care on risk for major osteoporotic fracture in patients with new onset rheumatoid arthritis |
title_full | Impact of continuity of care on risk for major osteoporotic fracture in patients with new onset rheumatoid arthritis |
title_fullStr | Impact of continuity of care on risk for major osteoporotic fracture in patients with new onset rheumatoid arthritis |
title_full_unstemmed | Impact of continuity of care on risk for major osteoporotic fracture in patients with new onset rheumatoid arthritis |
title_short | Impact of continuity of care on risk for major osteoporotic fracture in patients with new onset rheumatoid arthritis |
title_sort | impact of continuity of care on risk for major osteoporotic fracture in patients with new onset rheumatoid arthritis |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9205920/ https://www.ncbi.nlm.nih.gov/pubmed/35715560 http://dx.doi.org/10.1038/s41598-022-14368-7 |
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