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Impact of continuity of care on risk for major osteoporotic fracture in patients with new onset rheumatoid arthritis

There is a clear relationship between rheumatoid arthritis (RA) and major osteoporotic fracture (MOF), although there is limited evidence on the effect of continuity of care (COC) on MOF in these patients. We investigated the association between COC and risk of MOF, including fractures of the lumbar...

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Autores principales: Kim, Seung Hoon, Kim, Hyunkyu, Jeong, Sung Hoon, Jang, Suk-Yong, Park, Eun-Cheol
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9205920/
https://www.ncbi.nlm.nih.gov/pubmed/35715560
http://dx.doi.org/10.1038/s41598-022-14368-7
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author Kim, Seung Hoon
Kim, Hyunkyu
Jeong, Sung Hoon
Jang, Suk-Yong
Park, Eun-Cheol
author_facet Kim, Seung Hoon
Kim, Hyunkyu
Jeong, Sung Hoon
Jang, Suk-Yong
Park, Eun-Cheol
author_sort Kim, Seung Hoon
collection PubMed
description There is a clear relationship between rheumatoid arthritis (RA) and major osteoporotic fracture (MOF), although there is limited evidence on the effect of continuity of care (COC) on MOF in these patients. We investigated the association between COC and risk of MOF, including fractures of the lumbar spine and pelvis, forearm, and hip, among newly diagnosed RA patients aged ≥ 60 years. A total of 8715 incident RA patients from 2004 to 2010 were included from the Korean National Health Insurance Service-Senior cohort database. Participants were categorized into a good and bad COC group according to the COC index. The cumulative incidence of MOF was higher in RA patients with bad than in those with good COC (p < 0.001). The incidence rates of MOF were 4439 and 3275 cases per 100,000 person-years in patients with bad and good COC, respectively. RA patients with bad COC had an increased incidence of overall MOF (adjusted hazard ratio, 1.32; 95% confidence interval, 1.14–1.53), with the highest increase in risk being that of forearm fracture. An increased MOF risk in patients with bad COC was predominantly observed in females. This study suggested that interventions that can improve COC in patients with RA should be considered.
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spelling pubmed-92059202022-06-19 Impact of continuity of care on risk for major osteoporotic fracture in patients with new onset rheumatoid arthritis Kim, Seung Hoon Kim, Hyunkyu Jeong, Sung Hoon Jang, Suk-Yong Park, Eun-Cheol Sci Rep Article There is a clear relationship between rheumatoid arthritis (RA) and major osteoporotic fracture (MOF), although there is limited evidence on the effect of continuity of care (COC) on MOF in these patients. We investigated the association between COC and risk of MOF, including fractures of the lumbar spine and pelvis, forearm, and hip, among newly diagnosed RA patients aged ≥ 60 years. A total of 8715 incident RA patients from 2004 to 2010 were included from the Korean National Health Insurance Service-Senior cohort database. Participants were categorized into a good and bad COC group according to the COC index. The cumulative incidence of MOF was higher in RA patients with bad than in those with good COC (p < 0.001). The incidence rates of MOF were 4439 and 3275 cases per 100,000 person-years in patients with bad and good COC, respectively. RA patients with bad COC had an increased incidence of overall MOF (adjusted hazard ratio, 1.32; 95% confidence interval, 1.14–1.53), with the highest increase in risk being that of forearm fracture. An increased MOF risk in patients with bad COC was predominantly observed in females. This study suggested that interventions that can improve COC in patients with RA should be considered. Nature Publishing Group UK 2022-06-17 /pmc/articles/PMC9205920/ /pubmed/35715560 http://dx.doi.org/10.1038/s41598-022-14368-7 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Kim, Seung Hoon
Kim, Hyunkyu
Jeong, Sung Hoon
Jang, Suk-Yong
Park, Eun-Cheol
Impact of continuity of care on risk for major osteoporotic fracture in patients with new onset rheumatoid arthritis
title Impact of continuity of care on risk for major osteoporotic fracture in patients with new onset rheumatoid arthritis
title_full Impact of continuity of care on risk for major osteoporotic fracture in patients with new onset rheumatoid arthritis
title_fullStr Impact of continuity of care on risk for major osteoporotic fracture in patients with new onset rheumatoid arthritis
title_full_unstemmed Impact of continuity of care on risk for major osteoporotic fracture in patients with new onset rheumatoid arthritis
title_short Impact of continuity of care on risk for major osteoporotic fracture in patients with new onset rheumatoid arthritis
title_sort impact of continuity of care on risk for major osteoporotic fracture in patients with new onset rheumatoid arthritis
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9205920/
https://www.ncbi.nlm.nih.gov/pubmed/35715560
http://dx.doi.org/10.1038/s41598-022-14368-7
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