Mebendazole, an anti-helminth drug, suppresses inflammation, oxidative stress and injury in a mouse model of ulcerative colitis

Mebendazole (MBZ) is an efficacious anthelmintic with known anti-inflammatory and fibrinolytic properties. In this study, we aimed to explore the protective effects of this FDA-approved drug against DSS-induced colitis in a murine model either alone or in combination with Sulfasalazine (SSZ), a stan...

Descripción completa

Detalles Bibliográficos
Autores principales: Eskandari, Moein, Asgharzadeh, Fereshteh, Askarnia-faal, Mohammad Mostafa, Naimi, Hamideh, Avan, Amir, Ahadi, Mitra, Vossoughinia, Hassan, Gharib, Masoumeh, Soleimani, Atena, Naghibzadeh, Niloufar, Ferns, Gordon, Ryzhikov, Mikhail, Khazaei, Majid, Hassanian, Seyed Mahdi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9205960/
https://www.ncbi.nlm.nih.gov/pubmed/35715495
http://dx.doi.org/10.1038/s41598-022-14420-6

Ejemplares similares

Ejemplares similares