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Extra-neural signals from severed nerves enable intrinsic hand movements in transhumeral amputations
Robotic prostheses controlled by myoelectric signals can restore limited but important hand function in individuals with upper limb amputation. The lack of individual finger control highlights the yet insurmountable gap to fully replacing a biological hand. Implanted electrodes around severed nerves...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9206000/ https://www.ncbi.nlm.nih.gov/pubmed/35715459 http://dx.doi.org/10.1038/s41598-022-13363-2 |
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author | Ahkami, Bahareh Mastinu, Enzo Earley, Eric J. Ortiz-Catalan, Max |
author_facet | Ahkami, Bahareh Mastinu, Enzo Earley, Eric J. Ortiz-Catalan, Max |
author_sort | Ahkami, Bahareh |
collection | PubMed |
description | Robotic prostheses controlled by myoelectric signals can restore limited but important hand function in individuals with upper limb amputation. The lack of individual finger control highlights the yet insurmountable gap to fully replacing a biological hand. Implanted electrodes around severed nerves have been used to elicit sensations perceived as arising from the missing limb, but using such extra-neural electrodes to record motor signals that allow for the decoding of phantom movements has remained elusive. Here, we showed the feasibility of using signals from non-penetrating neural electrodes to decode intrinsic hand and finger movements in individuals with above-elbow amputations. We found that information recorded with extra-neural electrodes alone was enough to decode phantom hand and individual finger movements, and as expected, the addition of myoelectric signals reduced classification errors both in offline and in real-time decoding. |
format | Online Article Text |
id | pubmed-9206000 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-92060002022-06-19 Extra-neural signals from severed nerves enable intrinsic hand movements in transhumeral amputations Ahkami, Bahareh Mastinu, Enzo Earley, Eric J. Ortiz-Catalan, Max Sci Rep Article Robotic prostheses controlled by myoelectric signals can restore limited but important hand function in individuals with upper limb amputation. The lack of individual finger control highlights the yet insurmountable gap to fully replacing a biological hand. Implanted electrodes around severed nerves have been used to elicit sensations perceived as arising from the missing limb, but using such extra-neural electrodes to record motor signals that allow for the decoding of phantom movements has remained elusive. Here, we showed the feasibility of using signals from non-penetrating neural electrodes to decode intrinsic hand and finger movements in individuals with above-elbow amputations. We found that information recorded with extra-neural electrodes alone was enough to decode phantom hand and individual finger movements, and as expected, the addition of myoelectric signals reduced classification errors both in offline and in real-time decoding. Nature Publishing Group UK 2022-06-17 /pmc/articles/PMC9206000/ /pubmed/35715459 http://dx.doi.org/10.1038/s41598-022-13363-2 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Article Ahkami, Bahareh Mastinu, Enzo Earley, Eric J. Ortiz-Catalan, Max Extra-neural signals from severed nerves enable intrinsic hand movements in transhumeral amputations |
title | Extra-neural signals from severed nerves enable intrinsic hand movements in transhumeral amputations |
title_full | Extra-neural signals from severed nerves enable intrinsic hand movements in transhumeral amputations |
title_fullStr | Extra-neural signals from severed nerves enable intrinsic hand movements in transhumeral amputations |
title_full_unstemmed | Extra-neural signals from severed nerves enable intrinsic hand movements in transhumeral amputations |
title_short | Extra-neural signals from severed nerves enable intrinsic hand movements in transhumeral amputations |
title_sort | extra-neural signals from severed nerves enable intrinsic hand movements in transhumeral amputations |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9206000/ https://www.ncbi.nlm.nih.gov/pubmed/35715459 http://dx.doi.org/10.1038/s41598-022-13363-2 |
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