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Signaling Mechanism for Modulation by GLP-1 and Exendin-4 of GABA Receptors on Rat Retinal Ganglion Cells
Glucagon-like peptide-1 (GLP-1) is expressed in retinal neurons, but its role in the retina is largely unknown. Here, we demonstrated that GLP-1 or the GLP-1 receptor (GLP-1R; a G protein-coupled receptor) agonist exendin-4 suppressed γ-aminobutyric acid receptor (GABAR)-mediated currents through GL...
Autores principales: | Zhang, Tao, Ruan, Hang-Ze, Wang, Yong-Chen, Shao, Yu-Qi, Zhou, Wei, Weng, Shi-Jun, Zhong, Yong-Mei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Nature Singapore
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9206055/ https://www.ncbi.nlm.nih.gov/pubmed/35278196 http://dx.doi.org/10.1007/s12264-022-00826-9 |
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