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Ligand-based and structure-based studies to develop predictive models for SARS-CoV-2 main protease inhibitors through the 3d-qsar.com portal

The main protease (M(pro)) of SARS-Cov-2 is the essential enzyme for maturation of functional proteins implicated in viral replication and transcription. The peculiarity of its specific cleavage site joint with its high degree of conservation among all coronaviruses promote it as an attractive targe...

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Detalles Bibliográficos
Autores principales:	Proia, Eleonora, Ragno, Alessio, Antonini, Lorenzo, Sabatino, Manuela, Mladenovič, Milan, Capobianco, Roberto, Ragno, Rino
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer International Publishing 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9206107/ https://www.ncbi.nlm.nih.gov/pubmed/35716228 http://dx.doi.org/10.1007/s10822-022-00460-7

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