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MIF/CXCR4 signaling axis contributes to survival, invasion, and drug resistance of metastatic neuroblastoma cells in the bone marrow microenvironment
BACKGROUND: The bone marrow (BM) is the most common site of dissemination in patients with aggressive, metastatic neuroblastoma (NB). However, the molecular mechanisms underlying the aggressive behavior of NB cells in the BM niche are still greatly unknown. In the present study, we explored biologic...
Autores principales: | Garcia-Gerique, Laura, García, Marta, Garrido-Garcia, Alícia, Gómez-González, Soledad, Torrebadell, Montserrat, Prada, Estela, Pascual-Pasto, Guillem, Muñoz, Oscar, Perez-Jaume, Sara, Lemos, Isadora, Salvador, Noelia, Vila-Ubach, Monica, Doncel-Requena, Ana, Suñol, Mariona, Carcaboso, Angel M., Mora, Jaume, Lavarino, Cinzia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9206243/ https://www.ncbi.nlm.nih.gov/pubmed/35715791 http://dx.doi.org/10.1186/s12885-022-09725-8 |
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