Cargando…
RCAN1-mediated calcineurin inhibition as a target for cancer therapy
Cancer is the leading cause of mortality worldwide. Regulator of calcineurin 1 (RCAN1), as a patent endogenous inhibitor of calcineurin, plays crucial roles in the pathogenesis of cancers. Except for hypopharyngeal and laryngopharynx cancer, high expression of RCAN1 inhibits tumor progression. Molec...
Autores principales: | Lao, Mengyi, Zhang, Xiaozhen, Yang, Hanshen, Bai, Xueli, Liang, Tingbo |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9206313/ https://www.ncbi.nlm.nih.gov/pubmed/35717152 http://dx.doi.org/10.1186/s10020-022-00492-7 |
Ejemplares similares
-
Regulator of calcineurin 1 gene isoform 4 in pancreatic ductal adenocarcinoma regulates the progression of tumor cells
por: Lao, Mengyi, et al.
Publicado: (2021) -
The structure of the RCAN1:CN complex explains the inhibition of and substrate recruitment by calcineurin
por: Li, Yang, et al.
Publicado: (2020) -
RCAN1 in cardiovascular diseases: molecular mechanisms and a potential therapeutic target
por: Wang, Shuai, et al.
Publicado: (2020) -
Combination cancer immunotherapy targeting TNFR2 and PD-1/PD-L1 signaling reduces immunosuppressive effects in the microenvironment of pancreatic tumors
por: Zhang, Xiaozhen, et al.
Publicado: (2022) -
Regulator of Calcineurin (RCAN): Beyond Down Syndrome Critical Region
por: Lee, Sun-Kyung, et al.
Publicado: (2020)