Cargando…

Impact of sarcopenia on intertrochanteric femoral fracture in the elderly

OBJECTIVE: The aim of this study was to investigate the effect of skeletal sarcopenia on the prognosis of intertrochanteric fracture in the elderly. METHODS: We collected information on 144 patients with femoral intertrochanteric fracture (FIF). The influence of sarcopenia on the chance of death was...

Descripción completa

Detalles Bibliográficos
Autores principales: Jiang, Shunli, Ding, Yu, Kang, Lixing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9206433/
https://www.ncbi.nlm.nih.gov/pubmed/35726258
http://dx.doi.org/10.7717/peerj.13445
_version_ 1784729336353390592
author Jiang, Shunli
Ding, Yu
Kang, Lixing
author_facet Jiang, Shunli
Ding, Yu
Kang, Lixing
author_sort Jiang, Shunli
collection PubMed
description OBJECTIVE: The aim of this study was to investigate the effect of skeletal sarcopenia on the prognosis of intertrochanteric fracture in the elderly. METHODS: We collected information on 144 patients with femoral intertrochanteric fracture (FIF). The influence of sarcopenia on the chance of death was determined using binary Probit regression analysis. For additional analysis, the Chow test was utilized to select the best distinguishing node in the instrumental activities of daily living (IADL) score. We looked for characteristics that were linked to a higher probability of death and a poor IADL outcome within 1 year. The data collected above were analyzed using logistic regression analysis. The internal calibration degree and model validity were assessed by GiViTI calibration. RESULTS: Sarcopenia, EuroQol-5D 1 month score, age, gender, and hypertension were identified as risk factors for death in older patients with FIF within a year by logistic regression analysis. Sarcopenia, psychotropics, BMI, and length of hospital stay were all found to be risk factors for poor IADL outcomes (P < 0.1). The calibration curves indicated that the anticipated and actual probabilities of these two models were very close. The study’s reliability coefficient was 0.671, showing a satisfactory level of reliability. CONCLUSION: In elderly patients with FIF, sarcopenia, EuroQol-5D score, age, gender, and hypertension were risk factors for death; sarcopenia, hospital stay length, BMI were risk factors for poor quality of life.
format Online
Article
Text
id pubmed-9206433
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher PeerJ Inc.
record_format MEDLINE/PubMed
spelling pubmed-92064332022-06-19 Impact of sarcopenia on intertrochanteric femoral fracture in the elderly Jiang, Shunli Ding, Yu Kang, Lixing PeerJ Orthopedics OBJECTIVE: The aim of this study was to investigate the effect of skeletal sarcopenia on the prognosis of intertrochanteric fracture in the elderly. METHODS: We collected information on 144 patients with femoral intertrochanteric fracture (FIF). The influence of sarcopenia on the chance of death was determined using binary Probit regression analysis. For additional analysis, the Chow test was utilized to select the best distinguishing node in the instrumental activities of daily living (IADL) score. We looked for characteristics that were linked to a higher probability of death and a poor IADL outcome within 1 year. The data collected above were analyzed using logistic regression analysis. The internal calibration degree and model validity were assessed by GiViTI calibration. RESULTS: Sarcopenia, EuroQol-5D 1 month score, age, gender, and hypertension were identified as risk factors for death in older patients with FIF within a year by logistic regression analysis. Sarcopenia, psychotropics, BMI, and length of hospital stay were all found to be risk factors for poor IADL outcomes (P < 0.1). The calibration curves indicated that the anticipated and actual probabilities of these two models were very close. The study’s reliability coefficient was 0.671, showing a satisfactory level of reliability. CONCLUSION: In elderly patients with FIF, sarcopenia, EuroQol-5D score, age, gender, and hypertension were risk factors for death; sarcopenia, hospital stay length, BMI were risk factors for poor quality of life. PeerJ Inc. 2022-06-15 /pmc/articles/PMC9206433/ /pubmed/35726258 http://dx.doi.org/10.7717/peerj.13445 Text en © 2022 Jiang et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, reproduction and adaptation in any medium and for any purpose provided that it is properly attributed. For attribution, the original author(s), title, publication source (PeerJ) and either DOI or URL of the article must be cited.
spellingShingle Orthopedics
Jiang, Shunli
Ding, Yu
Kang, Lixing
Impact of sarcopenia on intertrochanteric femoral fracture in the elderly
title Impact of sarcopenia on intertrochanteric femoral fracture in the elderly
title_full Impact of sarcopenia on intertrochanteric femoral fracture in the elderly
title_fullStr Impact of sarcopenia on intertrochanteric femoral fracture in the elderly
title_full_unstemmed Impact of sarcopenia on intertrochanteric femoral fracture in the elderly
title_short Impact of sarcopenia on intertrochanteric femoral fracture in the elderly
title_sort impact of sarcopenia on intertrochanteric femoral fracture in the elderly
topic Orthopedics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9206433/
https://www.ncbi.nlm.nih.gov/pubmed/35726258
http://dx.doi.org/10.7717/peerj.13445
work_keys_str_mv AT jiangshunli impactofsarcopeniaonintertrochantericfemoralfractureintheelderly
AT dingyu impactofsarcopeniaonintertrochantericfemoralfractureintheelderly
AT kanglixing impactofsarcopeniaonintertrochantericfemoralfractureintheelderly