Cargando…

Comparative Study of Macular Vascular Density and Retinal Thickness in Myopia Children with Different Microscope Diopters Based on OCTA

In order to study the vascular density and retinal thickness of myopic children, a depth study was carried out on the basis of OCTA microscope. Through the methods of prospective cross-sectional research, statistical analysis, and basic data comparison, the research examination of myopia children un...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Meiling, Zhao, Fanning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9206553/
https://www.ncbi.nlm.nih.gov/pubmed/35811761
http://dx.doi.org/10.1155/2022/5038918
_version_ 1784729354901651456
author Chen, Meiling
Zhao, Fanning
author_facet Chen, Meiling
Zhao, Fanning
author_sort Chen, Meiling
collection PubMed
description In order to study the vascular density and retinal thickness of myopic children, a depth study was carried out on the basis of OCTA microscope. Through the methods of prospective cross-sectional research, statistical analysis, and basic data comparison, the research examination of myopia children under OCTA was successfully analyzed. There were significant differences in the density of superficial capillaries in the whole macular region, inner ring, temporal side of inner ring, and nasal side (P = 0.033, 0.024, 0.018, 0.032), and there was no significant difference in other ranges (P > 0.05). Macular fovea, as the most sensitive part of the retina, has pathological changes, which will also lead to serious negative effects on vision. The limitations of cross-sectional studies include the results of a relatively small sample size. After the study of OCTA in the macular region of children with myopia, it is related to the progressive atrophy of the retina and choroid in the macular region. When there are obvious pathological changes in the macular region, the thickness of the macular region becomes significantly thinner. We found that there was a positive correlation between retinal vascular density and retinal thickness in the fovea and above of myopia. The retinal thickness of the whole macular region, the inner ring and its four quadrants, and the outer ring and its four quadrants were positively correlated with SE (standard error) (all P < 0.05); Foveal ring retinal thickness was not associated with SE.
format Online
Article
Text
id pubmed-9206553
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Hindawi
record_format MEDLINE/PubMed
spelling pubmed-92065532022-07-08 Comparative Study of Macular Vascular Density and Retinal Thickness in Myopia Children with Different Microscope Diopters Based on OCTA Chen, Meiling Zhao, Fanning Scanning Research Article In order to study the vascular density and retinal thickness of myopic children, a depth study was carried out on the basis of OCTA microscope. Through the methods of prospective cross-sectional research, statistical analysis, and basic data comparison, the research examination of myopia children under OCTA was successfully analyzed. There were significant differences in the density of superficial capillaries in the whole macular region, inner ring, temporal side of inner ring, and nasal side (P = 0.033, 0.024, 0.018, 0.032), and there was no significant difference in other ranges (P > 0.05). Macular fovea, as the most sensitive part of the retina, has pathological changes, which will also lead to serious negative effects on vision. The limitations of cross-sectional studies include the results of a relatively small sample size. After the study of OCTA in the macular region of children with myopia, it is related to the progressive atrophy of the retina and choroid in the macular region. When there are obvious pathological changes in the macular region, the thickness of the macular region becomes significantly thinner. We found that there was a positive correlation between retinal vascular density and retinal thickness in the fovea and above of myopia. The retinal thickness of the whole macular region, the inner ring and its four quadrants, and the outer ring and its four quadrants were positively correlated with SE (standard error) (all P < 0.05); Foveal ring retinal thickness was not associated with SE. Hindawi 2022-06-11 /pmc/articles/PMC9206553/ /pubmed/35811761 http://dx.doi.org/10.1155/2022/5038918 Text en Copyright © 2022 Meiling Chen and Fanning Zhao. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Chen, Meiling
Zhao, Fanning
Comparative Study of Macular Vascular Density and Retinal Thickness in Myopia Children with Different Microscope Diopters Based on OCTA
title Comparative Study of Macular Vascular Density and Retinal Thickness in Myopia Children with Different Microscope Diopters Based on OCTA
title_full Comparative Study of Macular Vascular Density and Retinal Thickness in Myopia Children with Different Microscope Diopters Based on OCTA
title_fullStr Comparative Study of Macular Vascular Density and Retinal Thickness in Myopia Children with Different Microscope Diopters Based on OCTA
title_full_unstemmed Comparative Study of Macular Vascular Density and Retinal Thickness in Myopia Children with Different Microscope Diopters Based on OCTA
title_short Comparative Study of Macular Vascular Density and Retinal Thickness in Myopia Children with Different Microscope Diopters Based on OCTA
title_sort comparative study of macular vascular density and retinal thickness in myopia children with different microscope diopters based on octa
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9206553/
https://www.ncbi.nlm.nih.gov/pubmed/35811761
http://dx.doi.org/10.1155/2022/5038918
work_keys_str_mv AT chenmeiling comparativestudyofmacularvasculardensityandretinalthicknessinmyopiachildrenwithdifferentmicroscopedioptersbasedonocta
AT zhaofanning comparativestudyofmacularvasculardensityandretinalthicknessinmyopiachildrenwithdifferentmicroscopedioptersbasedonocta