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Comparative genomic analysis of Streptomyces rapamycinicus NRRL 5491 and its mutant overproducing rapamycin

Streptomyces rapamycinicus NRRL 5491 is a well-known producer of rapamycin, a secondary metabolite with useful bioactivities, including antifungal, antitumor, and immunosuppressive functions. For the enhanced rapamycin production, a rapamycin-overproducing strain SRMK07 was previously obtained as a...

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Detalles Bibliográficos
Autores principales: Jo, Hee-Geun, Adidjaja, Joshua Julio, Kim, Do-Kyung, Park, Bu-Soo, Lee, Namil, Cho, Byung-Kwan, Kim, Hyun Uk, Oh, Min-Kyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9206652/
https://www.ncbi.nlm.nih.gov/pubmed/35717543
http://dx.doi.org/10.1038/s41598-022-14199-6

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