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Complex regulation of Gephyrin splicing is a determinant of inhibitory postsynaptic diversity
Gephyrin (GPHN) regulates the clustering of postsynaptic components at inhibitory synapses and is involved in pathophysiology of neuropsychiatric disorders. Here, we uncover an extensive diversity of GPHN transcripts that are tightly controlled by splicing during mouse and human brain development. P...
Autores principales: | Dos Reis, Raphaël, Kornobis, Etienne, Pereira, Alyssa, Tores, Frederic, Carrasco, Judit, Gautier, Candice, Jahannault-Talignani, Céline, Nitschké, Patrick, Muchardt, Christian, Schlosser, Andreas, Maric, Hans Michael, Ango, Fabrice, Allemand, Eric |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9206673/ https://www.ncbi.nlm.nih.gov/pubmed/35717442 http://dx.doi.org/10.1038/s41467-022-31264-w |
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