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A case report on zinc phosphide ingestion resulting to acute pancreatitis

Zinc phosphide is commonly used as a rodenticide and often abused for intentional self harm. For years, Scientist believed that, It gets converted to phosphine gas by hydrolysis in acidic circumference of the stomach upon ingestion. It is absorbed into the bloodstream and can affect cardiovascular,...

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Detalles Bibliográficos
Autores principales: Bhandari, Rupa, Basnet, Krity
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9207063/
https://www.ncbi.nlm.nih.gov/pubmed/35734667
http://dx.doi.org/10.1016/j.amsu.2022.103859
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author Bhandari, Rupa
Basnet, Krity
author_facet Bhandari, Rupa
Basnet, Krity
author_sort Bhandari, Rupa
collection PubMed
description Zinc phosphide is commonly used as a rodenticide and often abused for intentional self harm. For years, Scientist believed that, It gets converted to phosphine gas by hydrolysis in acidic circumference of the stomach upon ingestion. It is absorbed into the bloodstream and can affect cardiovascular, respiratory, hepato-biliary hematological and gastrointestinal tract. It also results into electrolyte imbalance and ultimately leads to multi organ failure. We present a case of 46 year-old-male with acute pancreatitis due to zinc phosphide ingestion that was successfully treated conservatively. Acute pancreatitis is a rare complication of zinc phosphide poisoning. It is crucial to identify zinc phosphide as the cause of acute pancreatitis and rule out other factors (like alcohol, drugs, genetics) contributing to acute pancreatitis. Interestingly, patient presents with only mild symptoms of poisoning as metabolic acidosis and abdominal discomfort, acute pancreatitis was incidentally diagnosed through lab investigations and radiographs reports after 3–4 days of ongoing conservative treatment. Management was conservative for acute pancreatitis. This article provides a comprehensive review of management of zinc phosphide poisoning induced acute pancreatitis.
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spelling pubmed-92070632022-06-21 A case report on zinc phosphide ingestion resulting to acute pancreatitis Bhandari, Rupa Basnet, Krity Ann Med Surg (Lond) Case Report Zinc phosphide is commonly used as a rodenticide and often abused for intentional self harm. For years, Scientist believed that, It gets converted to phosphine gas by hydrolysis in acidic circumference of the stomach upon ingestion. It is absorbed into the bloodstream and can affect cardiovascular, respiratory, hepato-biliary hematological and gastrointestinal tract. It also results into electrolyte imbalance and ultimately leads to multi organ failure. We present a case of 46 year-old-male with acute pancreatitis due to zinc phosphide ingestion that was successfully treated conservatively. Acute pancreatitis is a rare complication of zinc phosphide poisoning. It is crucial to identify zinc phosphide as the cause of acute pancreatitis and rule out other factors (like alcohol, drugs, genetics) contributing to acute pancreatitis. Interestingly, patient presents with only mild symptoms of poisoning as metabolic acidosis and abdominal discomfort, acute pancreatitis was incidentally diagnosed through lab investigations and radiographs reports after 3–4 days of ongoing conservative treatment. Management was conservative for acute pancreatitis. This article provides a comprehensive review of management of zinc phosphide poisoning induced acute pancreatitis. Elsevier 2022-05-24 /pmc/articles/PMC9207063/ /pubmed/35734667 http://dx.doi.org/10.1016/j.amsu.2022.103859 Text en © 2022 The Author https://creativecommons.org/licenses/by/4.0/This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Case Report
Bhandari, Rupa
Basnet, Krity
A case report on zinc phosphide ingestion resulting to acute pancreatitis
title A case report on zinc phosphide ingestion resulting to acute pancreatitis
title_full A case report on zinc phosphide ingestion resulting to acute pancreatitis
title_fullStr A case report on zinc phosphide ingestion resulting to acute pancreatitis
title_full_unstemmed A case report on zinc phosphide ingestion resulting to acute pancreatitis
title_short A case report on zinc phosphide ingestion resulting to acute pancreatitis
title_sort case report on zinc phosphide ingestion resulting to acute pancreatitis
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9207063/
https://www.ncbi.nlm.nih.gov/pubmed/35734667
http://dx.doi.org/10.1016/j.amsu.2022.103859
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