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Kimura's disease and its masquerade with a malignancy: A case report

Kimura's disease is an uncommon chronic condition that often masquerades as a malignancy. It is reported predominantly in males of South-East Asia in their second and third decade of life. Most of the patients present with increased eosinophilia, follicular hyperplasia and high levels of IgE ci...

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Autores principales: Farooqui, Fareeha, Rehman, Ibad ur, Waseem, Sania, Ullah, Irfan, Jehan, Mehar, Asghar, Muhammad Sohaib
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9207072/
https://www.ncbi.nlm.nih.gov/pubmed/35734712
http://dx.doi.org/10.1016/j.amsu.2022.103864
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author Farooqui, Fareeha
Rehman, Ibad ur
Waseem, Sania
Ullah, Irfan
Jehan, Mehar
Asghar, Muhammad Sohaib
author_facet Farooqui, Fareeha
Rehman, Ibad ur
Waseem, Sania
Ullah, Irfan
Jehan, Mehar
Asghar, Muhammad Sohaib
author_sort Farooqui, Fareeha
collection PubMed
description Kimura's disease is an uncommon chronic condition that often masquerades as a malignancy. It is reported predominantly in males of South-East Asia in their second and third decade of life. Most of the patients present with increased eosinophilia, follicular hyperplasia and high levels of IgE circulating in their blood. In this case, we report a patient of 29 years age who presented with complaints of left parotid and left post-auricular swellings. It was painless and growing gradually in size over the period of 8 years. It was asymptomatic during the whole period of the disease. Patient was diagnosed on histology and subsequent immunohistochemistry reports. Treatment in this patient included parotidectomy and lymph node dissection. It was followed by local radiation to prevent recurrence. It can be concluded that Kimura's disease may vary in its presentation but a few features remain characteristic. No reports of malignant change have been reported as of yet making its prognosis quite favorable for the patient. Surgery remains the choice of treatment but for more effective approach, it should be followed by radiation.
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spelling pubmed-92070722022-06-21 Kimura's disease and its masquerade with a malignancy: A case report Farooqui, Fareeha Rehman, Ibad ur Waseem, Sania Ullah, Irfan Jehan, Mehar Asghar, Muhammad Sohaib Ann Med Surg (Lond) Case Report Kimura's disease is an uncommon chronic condition that often masquerades as a malignancy. It is reported predominantly in males of South-East Asia in their second and third decade of life. Most of the patients present with increased eosinophilia, follicular hyperplasia and high levels of IgE circulating in their blood. In this case, we report a patient of 29 years age who presented with complaints of left parotid and left post-auricular swellings. It was painless and growing gradually in size over the period of 8 years. It was asymptomatic during the whole period of the disease. Patient was diagnosed on histology and subsequent immunohistochemistry reports. Treatment in this patient included parotidectomy and lymph node dissection. It was followed by local radiation to prevent recurrence. It can be concluded that Kimura's disease may vary in its presentation but a few features remain characteristic. No reports of malignant change have been reported as of yet making its prognosis quite favorable for the patient. Surgery remains the choice of treatment but for more effective approach, it should be followed by radiation. Elsevier 2022-05-27 /pmc/articles/PMC9207072/ /pubmed/35734712 http://dx.doi.org/10.1016/j.amsu.2022.103864 Text en © 2022 The Authors https://creativecommons.org/licenses/by/4.0/This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Case Report
Farooqui, Fareeha
Rehman, Ibad ur
Waseem, Sania
Ullah, Irfan
Jehan, Mehar
Asghar, Muhammad Sohaib
Kimura's disease and its masquerade with a malignancy: A case report
title Kimura's disease and its masquerade with a malignancy: A case report
title_full Kimura's disease and its masquerade with a malignancy: A case report
title_fullStr Kimura's disease and its masquerade with a malignancy: A case report
title_full_unstemmed Kimura's disease and its masquerade with a malignancy: A case report
title_short Kimura's disease and its masquerade with a malignancy: A case report
title_sort kimura's disease and its masquerade with a malignancy: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9207072/
https://www.ncbi.nlm.nih.gov/pubmed/35734712
http://dx.doi.org/10.1016/j.amsu.2022.103864
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