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CaMK4 Promotes Acute Lung Injury Through NLRP3 Inflammasome Activation in Type II Alveolar Epithelial Cell

BACKGROUND: Type II alveolar epithelial cell (AEC II), in addition to its roles in maintaining lung homeostasis, takes an active role in inflammatory response during acute lung injury (ALI). Ca(2+)/calmodulin-dependent protein kinase IV (CaMK4) activated by Ca(2+)/calmodulin signaling, has been impl...

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Detalles Bibliográficos
Autores principales: Zhang, Tengyue, Li, Mengyuan, Zhao, Siyuan, Zhou, Mianjing, Liao, Huai, Wu, Haiyan, Mo, Xinyue, Wang, Hongxing, Guo, Chaohuan, Zhang, Hui, Yang, Niansheng, Huang, Yuefang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9207179/
https://www.ncbi.nlm.nih.gov/pubmed/35734175
http://dx.doi.org/10.3389/fimmu.2022.890710