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Harnessing Clinical Trial and Real-World Data Towards an Understanding of Sex Effects on Drug Pharmacokinetics, Pharmacodynamics and Efficacy
Increasing clinical data on sex-related differences in drug efficacy and toxicity has highlighted the importance of understanding the impact of sex on drug pharmacokinetics and pharmacodynamics. Intrinsic differences between males and females, such as different CYP enzyme activity, drug transporter...
Autores principales: | Oi Yan Chan, Joyce, Moullet, Marie, Williamson, Beth, Arends, Rosalinda H., Pilla Reddy, Venkatesh |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9207260/ https://www.ncbi.nlm.nih.gov/pubmed/35734405 http://dx.doi.org/10.3389/fphar.2022.874606 |
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