Case Report: Various Clinical Manifestations Caused by Varicella-Zoster Virus in a Family

A family cluster of varicella-zoster virus (VZV) infections was reported. Four family members (two children and their parents) continuously develop varicella after the grandmother’s herpes zoster. The unvaccinated 16-month-old infant and his mother developed primary varicella with atypical clinical...

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Detalles Bibliográficos
Autores principales: Meng, Qinghong, Wang, Bingsong, Zhang, Xianlai, Li, Zhen, Wang, Wenjie, Yao, Kaihu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pediatrics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9207272/
https://www.ncbi.nlm.nih.gov/pubmed/35733808
http://dx.doi.org/10.3389/fped.2022.876250
Descripción
Sumario:A family cluster of varicella-zoster virus (VZV) infections was reported. Four family members (two children and their parents) continuously develop varicella after the grandmother’s herpes zoster. The unvaccinated 16-month-old infant and his mother developed primary varicella with atypical clinical presentation; however, his 28-year-old father presented with a typical generalized vesicular rash. His vaccinated 4-year-old sister was clinically mild, which could be defined as a breakthrough varicella case. They infected the same virus strain but presented various clinical forms.

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